Researchers at Yale were the first to harness the reactivity of mustard gas by replacing the bivalent sulfur atom with a trivalent nitrogen atom.

Researchers at Yale were the first to harness the reactivity of mustard gas by replacing the bivalent sulfur atom with a trivalent nitrogen atom. Discuss how the reactivity of the resulting nitrogen mustards can be controlled to give a perfectly-tuned antineoplastic agent. You may draw and annotate structures to help explain your answer